REGULATION OF AKT PHOSPHORYLATION AT SER473 AND THR308 BY ENDOPLASMIC RETICULUM STRESS MODULATES SUBSTRATE SPECIFICITY IN A SEVERITY DEPENDENT MANNER.

Endoplasmic reticulum (ER) stress is a common 1036 factor in the pathophysiology of diverse human diseases that are characterised by contrasting cellular behaviours, from proliferation in cancer to apoptosis in neurodegenerative disorders.Coincidently, dysregulation of AKT/PKB activity, which is the central regulator of cell growth, proliferation a

We resolve the structural dynamics of the ultrafast photoinduced Mirrorless Camera ring opening reaction of 1,3-cyclohexadiene in space and time employing Echinacea megaelectronvolt gas phase ultrafast electron diffraction.We, furthermore, observe coherent large amplitude motions of the photoproduct.

In the remote sensing field, synthetic aperture radar (SAR) is a type of active microwave imaging sensor working in all-weather and all-day conditions, providing high-resolution SAR images of objects such as marine ships.Detection and instance segmentation of marine ships in SAR images has become an important question in remote sensing, but current